Tetraene Acetate (3TR) (cas 37413-91-5)
- CAS NO .:37413-91-5
- appearance: white or white-like powder
- content:≥ 99.0%
- Melting point: 168-178℃
- loss on drying:≤ 0.50%
- packing: net weight20kg/barrel
- use: steroid hormone drug intermediate
Compound Information: Tetraene Acetate (3TR) (CAS 37413-91-5)
| Category | Details |
|---|---|
| Name | Tetraene Acetate (3TR) |
| CAS Number | 37413-91-5 |
| Synonyms | 3,20-Dioxopregna-1,4,9(11),16-tetraen-21-yl acetate; 21-Acetoxypregna-1,4,9(11),16-tetraene-3,20-dione; Prednisone Impurity 12; 3TR |
| Molecular Formula | C₂₃H₃₀O₄ |
| Molecular Weight | 382.48 g/mol |
| Appearance | White or off-white crystalline powder |
| Purity | ≥99.0% (HPLC) |
| Melting Point | 168–178°C |
| Loss on Drying | ≤0.50% |
| Packaging | 20 kg/barrel |
| Storage | Sealed, dry, stored at 2–8°C |
| Solubility | Slightly soluble in DMSO |
| Usage | – Intermediate for dexamethasone, betamethasone, and triamcinolone synthesis. – Key precursor for anti-inflammatory delta-9,11 steroids (e.g., Vamorolone). |
Key Notes:
- Structural Role: Serves as a critical intermediate in steroid hormone drug synthesis, enabling acetylation at the 21-position for enhanced bioavailability.
- Quality Standards: Meets pharmaceutical purity requirements (≥99.0% HPLC).
- Supplier Information:
- Packaging: Bulk quantities available in 20 kg/barrel units.
- Storage: Requires airtight storage at controlled humidity and temperature (2–8°C).
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