Budesonide (cas 51333-22-3)

​Name Budesonide ​CAS 51333-22-3 ​Synonyms 1,4-PREGNADIEN-(R,S)-11-BETA,16-ALPHA,17,21-TETROL-3,20-DIONE CYCLIC 16,17 ACETAL; PULMICORT; RHINOCORT; Entocort CR; S-1320 等 ​EINECS (EC#) 257-139-7 ​Molecular Formula C₂₅H₃₄O₆ ​MDL Number MFCD00083259 ​Molecular Weight 430.53 ​Appearance White Solid ​Melting Point 221-232 °C (dec.) ​α (alpha) D25 +98.9° (c = 0.28 in methylene chloride) ​Boiling Point 464.79°C (rough estimate) ​Density 1.1046 g/cm³ (estimate) ​Refractive Index 1.4593 (estimate) ​Storage Temp. 2-8°C (避光保存) ​Solubility Practically insoluble in water; freely soluble in methylene chloride; sparingly soluble in ethanol (96%) ​Form Powder ​pKa 12.87 ± 0.10 (Predicted) ​Color White to Off-White ​Water Solubility 21.53 mg/L (25 °C) ​Usage Anti-inflammatory agent; treats asthma, COPD, Crohn’s disease, ulcerative colitis, allergic rhinitis, and nasal polyps. ​Merck Index 14,1468 ​BCS Class 2 (气雾剂), 1 (肠溶胶囊) ​InChIKey VOVIALXJUBGFJZ-KWVAZRHASA-N ​CAS Database Reference 51333-22-3