Cortisone Acetate (CAS 50-04-4)

​Name Cortisone acetate ​CAS 50-04-4 ​Synonyms 17,21-DIHYDROXYPREGN-4-ENE-3,11,20-TRIONE 21 ACETATE; 17ALPHA,21-DIHYDROXY-4-PREGNENE-3,11,20-TRIONE 21-ACETATE; 21-acetoxypregnen-17a-ol-3,11,20-trione; KENDALL’S COMPOUND ‘E’ ACETATE 等 ​EINECS (EC#) 200-006-5 ​Molecular Formula C₂₃H₃₀O₆ ​MDL Number MFCD00003609 ​Molecular Weight 402.48 ​Appearance Solid ​Melting Point 237-240 °C (lit.) ​α (alpha) D25 +164° (c = 0.5 in acetone); D25 +208 to +217° (dioxane) ​Boiling Point 577.3 ± 50.0 °C (Predicted) ​Density 1.26 ± 0.1 g/cm³ (Predicted) ​Refractive Index 212° (C=1, MeOH) ​Storage Temp. 2-8°C ​Solubility Practically insoluble in water; freely soluble in methylene chloride; sparingly soluble in acetone; slightly soluble in ethanol (96%) and methanol ​Form Solid ​pKa 12.32 ± 0.60 (Predicted) ​Color White to Off-White ​Stability Stable under proper storage; incompatible with strong oxidizing agents. ​Water Solubility 19 mg/L (25 °C) ​Usage Anti-inflammatory; immunosuppressant; used in treatment of adrenal insufficiency, arthritis, lupus, and allergic disorders 124 ​Merck Index 2539 ​BRN 2067543 ​CAS Database Reference 50-04-4