Tadalafil (CAS 171596-29-5)

Indications: Erectile dysfunction and pulmonary hypertension Pharmacology: It is a selective reversible inhibitor of guanosine cyclophosphate (cGMP)-specific phosphodiesterase 5 (PDE5).When sexual stimulation leads to the local release of nitric oxide, PDE5 is inhibited by tadalafil, which increases the level of cGMP in the cavernous body of the penis, which leads to relaxation of smooth muscles and blood flowing into the penis tissue to produce an erection, such as asexual stimulation. Compound Information : Cialis (Tadalafil) ​Category ​Details ​Name Cialis (Tadalafil) ​CAS Number 171596-29-5 ​Synonyms Tadalafil; (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methylpyrazino[1′,2′:1,6]pyrido[3,4-b]indole-1,4-dione; IC 351 ​EINECS Number 687-782-2 ​Molecular Formula C₂₂H₁₉N₃O₄ ​Molecular Weight 389.4 g/mol ​Chemical Properties – ​Appearance White to Off-White Crystalline Solid – ​Melting Point 298–300°C – ​Solubility DMSO (20 mg/mL, clear) – ​Form Powder – ​Color White to Beige – ​Stability Unstable in Methanol; store sealed in dry conditions at 2–8°C ​InChIKey WOXKDUGGOYFFRN-IIBYNOLFSA-N ​SMILES N1C2=C(C=CC=C2)C2C[C@]3([H])C(=O)N(C)CC(=O)N3C@HC1=2 ​Key Notes: ​Analytical & Handling Guidelines: