Nitenpyram (cas 150824-47-8)
Compound Information: Nitenpyram Category Details Name Nitenpyram CAS Number 150824-47-8 Synonyms Capstar, Bestguard, (E)-N-(6-Chloro-3-pyridylmethyl)-N-ethyl-N’-methyl-2-nitroethene-1,1-diamine EINECS Number 200-001-8 Molecular Formula C₁₁H₁₅ClN₄O₂ Molecular Weight 270.72 g/mol Physical Properties – Melting Point 83–84°C – Boiling Point 417.2 ± 45.0°C (predicted) – Density 1.254 ± 0.06 g/cm³ (predicted) – Solubility Slightly soluble in DMSO (250 mg/mL, requires ultrasonic treatment) – Form Light yellow to yellow powder – Stability Light-sensitive; store in inert atmosphere at 0–6°C Chemical Properties – pKa 2.46 ± 0.70 (predicted) Uses – Primary Use Nicotinic acetylcholine receptor agonist; insecticide for sucking pests – Targets Aphids, thrips, leafhoppers, whiteflies, and psyllids – Crop Applications Rice, vegetables, fruits, and tea – Veterinary Use Flea control in cats and dogs Mechanism of Action Interferes with insect nerve transmission by blocking nicotinic receptors Safety & Toxicity – Acute Toxicity – Rat LD₅₀ (oral): 1,680 mg/kg (male), 1,575 mg/kg (female) – Rat LD₅₀ (dermal): >2,000 mg/kg – Ecotoxicity – LC₅₀ (carp, 96 h): >1,000 mg/L – Harmful to bees, fish, and aquatic organisms Regulatory Notes – Precautions – Avoid contact with alkaline substances – Do not apply during flowering (7–14 days pre-harvest) – Resistance Rotate with non-neonicotinoid insecticides to delay resistance Supplier Information – Key Suppliers Sumitomo Chemical, Bayer CropScience, Sigma-Aldrich – Pricing ~$50–200/g (varies by purity and volume) Key Notes: