Rosuvastatin Calcium (cas 147098-20-2)
Indications: Adjuvant treatment for patients with primary hypercholesterolemia (typeaa, including heterozygous familial hypercholesterolemia) or mixed lipoproteinemia (typeⅡb) when diet or exercise therapy is not ideal.(Hypolipidemia) Pharmacology: Inhibit HMG-CoA reductase, reduce liver cell synthesis and storage of cholesterol, thereby reducing total blood cholesterol (TC) and LDL cholesterol Compound Information Table: Rosuvastatin Calcium Category Details Name Rosuvastatin Calcium CAS Number 147098-20-2 Synonyms CRESTOR; ROSUVASTATIN CA; ROSUVASTATIN CALCIUM; (3R,5S,6E)-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[N-methyl(n-methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic acid calcium salt EINECS Number 627-028-1 Molecular Formula C₄₄H₅₄CaF₂N₆O₁₂S₂ Molecular Weight 1001.14 g/mol Chemical Properties – Appearance White to Off-White Crystalline Solid – Melting Point 122°C – Optical Activity [α]/D +12 to +18° (c = 1 in methanol:water, 1:1) – Storage Temp. 2–8°C – Solubility DMSO (25 mg/mL, requires ultrasonic treatment); Water (1 mg/mL, requires ultrasonic treatment) – Form Powder – Color White to Beige InChIKey JSVIQRTVYKCCOM-LMRKSJJTNA-N Key Notes: Analytical & Formulation Guidelines: For spectral data (InChIKey: JSVIQRTVYKCCOM-LMRKSJJTNA-N) or pharmacokinetic studies, consult PubChem