9α-Hydroxyandrost -4-ene-3,17-dione (9α-OH-4AD) (cas 560-62-3)
9-hydroxy-4-androstene-3,17-dione Comprehensive Information Table Category Details Chemical Name 9-hydroxy-4-androstene-3,17-dione CAS Number 560-62-3 Synonyms 9-ALPHAHYDROXYANDROSTENEDIONE, 9α-hydroxyandrost-4-en-3,17-dione, (8S,9R,10S,13S,14S)-9-Hydroxy-10,13-dimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17(2H,6H)-dione Chemical Formula C₁₉H₂₆O₃ Molecular Weight 302.41 g/mol EINECS Number 611-349-9 Melting Point 222–223.5°C Boiling Point 470.3 ± 45.0°C (predicted) Density 1.19 ± 0.1 g/cm³ (predicted) Solubility Slightly soluble in water; practically insoluble in ethanol, acetone, and chloroform 38 Appearance White to off-white powder pKa 14.17 ± 0.60 (predicted) Optical Activity [α]²⁵/D +54° (c = 2 in H₂O) Key Applications & Pharmacological Properties Synthesis & Production Quality Control & Safety Parameter Specifications Purity ≥98% (HPLC) Impurities ≤0.5% total organic impurities Heavy Metals ≤10 ppm (Pb, Cd, Hg) Toxicity – LD₅₀ (mouse, oral): >5000 mg/kg– Irritation: Eyes, respiratory system, skin 12 Handling Precautions Wear gloves/face shields; avoid inhalation. Store under inert atmosphere. Regulatory Status Research & Development For detailed toxicology data or synthesis protocols, consult regulatory databases (e.g., FDA, EMA) or specialized pharmacological references.
