17alpha-Hydroxy-17β-cyanoandrost-4-en-3-on (cas 77881-13-1 )

17alpha-Hydroxy-17β-cyanoandrost-4-en-3-on (17α)-17-Hydroxy-3-oxoandrost-4-ene-17-carbonitrile Comprehensive Information Table ​Category ​Details ​Chemical Name (17α)-17-Hydroxy-3-oxoandrost-4-ene-17-carbonitrile ​CAS Number 77881-13-1 ​Synonyms Cyanohydrin matter, Androstenedione cyanohydrin, 17β-cyano-17α-hydroxyandrost-4-en-3-one ​Chemical Formula C₂₀H₂₇NO₂ ​Molecular Weight 313.43 ​EINECS Number 278-780-9 ​Melting Point 222–226°C ​Boiling Point 498.5 ± 45.0°C (predicted) ​Density 1.17 ± 0.1 g/cm³ (predicted) ​Vapor Pressure 0.001 Pa at 25°C ​pKa 11.20 ± 0.60 (predicted) ​Water Solubility 10 mg/L at 25°C ​Appearance White to off-white solid ​Optical Activity [α]²⁵/D +190° ±5° (c = 1 in chloroform) ​Applications ​Pharmaceutical Intermediate: Key precursor for synthesizing glucocorticoids and antiandrogenic agents.Research Use: Steroid metabolism studies and antineoplastic drug development. ​Hazard Classification Non-flammable ​Storage Conditions Sealed in dry, stored at 2–8°C ​Safety Information ​Risk Statements: R36/37/38 (irritating to eyes, respiratory system, skin)Precautionary Measures: S22 (Avoid inhalation), S24/25 (Avoid contact) ​MSDS Available from suppliers Supplementary Notes For detailed toxicological data or formulation protocols, consult specialized pharmacological references (e.g., PubChem, ChemSpider).