16α-Methyl Epoxide (8DM) (cas 24916-90-3)
Compound Information 16-beta Methyl Epoxide (CAS 24916-90-3) Category Details Name 16-beta Methyl Epoxide (16β-Methyl Epoxide) CAS Number 24916-90-3 Synonyms 16-ALPHA METHYL EPOXIDE; 9,11β-EPOXY-17,21-DIHYDROXY-16α-METHYL-PREGNA-1,4-DIENE-3,20-DIONE; 16β-Methyl Epoxide 21-Acetate; DB-11; 8-DM; Others listed in user data. Molecular Formula C₂₂H₂₈O₅ Molecular Weight 372.45 g/mol Appearance White to Pale Yellow Solid Melting Point 210-220°C Boiling Point 564.9 ± 50.0°C (Predicted) Density 1.32 g/cm³ Flash Point 198°C Solubility Slightly soluble in Chloroform (heated/sonicated), DMSO (sonicated), Methanol; Insoluble in water. Storage Sealed, dry, 2-8°C pKa 12.56 ± 0.70 (Predicted) Color White to Pale Yellow Applications – Metabolite of Mometasone Furoate.– Intermediate for anti-inflammatory drugs (e.g., Betamethasone).– Purity control reference for Dexamethasone. Preparation Derived from Hecogenin via epoxidation and esterification. Safety Irritant (Xi hazard code). Regulatory Compliant with hazardous material regulations (e.g., China HS Code: 2918990090). Key Notes: Let me know if you need additional details or formatting adjustments!