Estra-4,9-diene-3,17-dione (cas 5173-46-6)
CAS NO .:5173-46-6
- appearance: white or white-like powder
- content:≥ 98.0%
- Melting point:≥ 135 ℃
- loss on drying:≤ 0.50%
- packing: net weight25kg/barrel
- use: steroid hormone drug intermediate
Compound Information: Estra-4,9-diene-3,17-dione (CAS 5173-46-6)
| Category | Details |
|---|---|
| Name | Estra-4,9-diene-3,17-dione |
| CAS Number | 5173-46-6 |
| Synonyms | 19-norandrosta-4,9-diene-3,17-dione; 4,9-ESTRADIEN-3,17-DIONE; Methyldienedione; 17β-Hydroxy-17-methylestra-4,9-dien-3-one |
| Molecular Formula | C₁₈H₂₂O₂ |
| Molecular Weight | 270.37 g/mol |
| Appearance | Light beige solid |
| Melting Point | 131–134°C |
| Boiling Point | ~467°C (predicted) |
| Density | 1.16 g/cm³ (predicted) |
| Solubility | Sparingly soluble in organic solvents (e.g., DMSO, ethanol) |
| Storage | Refrigerated (2–8°C) |
| Usage | – Metabolite of STS 557 (Dienogest) – Antiglucocorticoid activity – Intermediate in steroid drug synthesis (e.g., Trenbolone) |
| Safety | – Classified as a controlled substance due to anabolic steroid properties – Handle with PPE (gloves, goggles) |
| Regulatory | – EU EINECS: 610-717-6 |
Key Notes:
- Chemical Structure:
- Features a 19-norsteroid backbone with a 4,9-diene system and a ketone group at position 3.
- The 17β-hydroxyl group contributes to its antiglucocorticoid activity.
- Applications:
- Used in veterinary medicine as a precursor for Trenbolone acetate, a potent anabolic steroid.
- Studied for potential metabolic modulation in hormone-related therapies.
- Supplier Information:
- Bulk Pricing: ~¥1–5/kg (varies by purity and order volume).
For analytical data (e.g., HPLC spectra), consult supplier technical documents or databases like PubChem.
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