Cortisone Acetate (CAS 50-04-4)
| Name | Cortisone acetate |
| CAS | 50-04-4 |
| Synonyms | 17,21-DIHYDROXYPREGN-4-ENE-3,11,20-TRIONE 21 ACETATE; 17ALPHA,21-DIHYDROXY-4-PREGNENE-3,11,20-TRIONE 21-ACETATE; 21-acetoxypregnen-17a-ol-3,11,20-trione; KENDALL’S COMPOUND ‘E’ ACETATE 等 |
| EINECS (EC#) | 200-006-5 |
| Molecular Formula | C₂₃H₃₀O₆ |
| MDL Number | MFCD00003609 |
| Molecular Weight | 402.48 |
| Appearance | Solid |
| Melting Point | 237-240 °C (lit.) |
| α (alpha) | D25 +164° (c = 0.5 in acetone); D25 +208 to +217° (dioxane) |
| Boiling Point | 577.3 ± 50.0 °C (Predicted) |
| Density | 1.26 ± 0.1 g/cm³ (Predicted) |
| Refractive Index | 212° (C=1, MeOH) |
| Storage Temp. | 2-8°C |
| Solubility | Practically insoluble in water; freely soluble in methylene chloride; sparingly soluble in acetone; slightly soluble in ethanol (96%) and methanol |
| Form | Solid |
| pKa | 12.32 ± 0.60 (Predicted) |
| Color | White to Off-White |
| Stability | Stable under proper storage; incompatible with strong oxidizing agents. |
| Water Solubility | 19 mg/L (25 °C) |
| Usage | Anti-inflammatory; immunosuppressant; used in treatment of adrenal insufficiency, arthritis, lupus, and allergic disorders 124 |
| Merck Index | 2539 |
| BRN | 2067543 |
| CAS Database Reference | 50-04-4 |
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