3aS,9aS,9bS)-4,5,8,9,9a,9b-hexahydro-3a-methyl-6-[2- (2,5,5-trimethyl-1,3-dioxan 2-yl)ethyl]-1H-Benz[e]indene- 3,7(2H,3aH)-dione

• CAS NO .:88128-61-4
• appearance: white or white-like powder
• content:≥ 98.0%
• loss on drying:≤ 0.50%
• packing: net weight25kg/barrel
• use: steroid hormone drug intermediate

Compound Information Table: 1H-Benz[e]indene-3,7(2H,3aH)-dione Derivative (CAS 88128-61-4)

​Key Notes:

1. ​Structural Features:
   • Contains a benz[e]indene core with a hexahydrocyclopenta[a]phenanthrene moiety and a trimethyl-substituted dioxane substituent.
   • Stereochemical designation ​**(3aS,9aS,9bS)** indicates a specific 3D configuration critical for biological activity.
2. ​Relevance:
   • Identified as ​Progesterone Impurity 33, often monitored in drug manufacturing to ensure purity standards (e.g., USP, EP).
   • Structurally related to synthetic intermediates in hormonal drug development.
3. ​Analytical Requirements:
   • Requires HPLC or LC-MS analysis for impurity profiling in pharmaceutical formulations.
   • Quality control focuses on residual solvent levels (e.g., dioxane derivatives).
4. ​Handling:
   • Avoid exposure to light and moisture; use airtight containers.

For spectral data or toxicity reports, consult databases like PubChem or supplier technical documents.